Director, Oncology Clinical Pharmacology Modeling And Simulation
GlaxoSmithKline
Cambridge, MA, US
Base: $188,100 to $313,500; bonus/equity: annual b...
2-3 days onsite
Phd in quantitative clinical pharmacology
5+ years mechanistic pkpd modeling experience
Proficiency in nonmem or r tools
GlaxoSmithKline (GSK) is seeking a Director for their Oncology Clinical Pharmacology Modeling and Simulation team, responsible for enhancing the development of innovative oncology therapies through quantitative excellence. This role requires a PhD in relevant disciplines and extensive experience in pharmacometrics, particularly in oncology
Job Summary
This role focuses on delivering quantitative excellence to inform and accelerate the development of innovative oncology therapies.
The position requires defining and executing model-based development strategies for oncology projects including exposure-response analysis and dose selection.
GSK offers a supportive environment with competitive compensation, annual bonuses, share-based incentives, and comprehensive health benefits.
Matching Summary
Match Score: 85
GlaxoSmithKline (GSK) is seeking a Director for their Oncology Clinical Pharmacology Modeling and Simulation team, responsible for enhancing the development of innovative oncology therapies through quantitative excellence. This role requires a PhD in relevant disciplines and extensive experience in pharmacometrics, particularly in oncology.
Salary
Base: $188,100 to $313,500; Bonus/Equity: Annual bonus and share-based long term incentive program; Benefits: Health care, retirement, paid holidays, vacation, and parental leave
Skills & Requirements
Must-have
PhD in Quantitative Clinical Pharmacology
5+ years mechanistic PKPD modeling experience
Proficiency in NONMEM or R tools
3+ years clinical data model-based analysis
Oncology therapeutic area expertise
Nice-to-have
Experience with AI/ML in pharmacometrics
Strong collaboration in multi-discipline teams
Track record of Model-Informed Drug Discovery
Ability to present to regulatory agencies
Knowledge of cancer mechanisms and endpoints
Key Requirements
PhD in Quantitative Clinical Pharmacology or PharmD with 4+ years experience
5+ years utilizing mechanistic PKPD and longitudinal disease modeling
Verifiable proficiency in NONMEM or R software
3+ years planning and reporting model-based clinical data analysis
On-site office presence required 2-3 days per week