Manifold Bio builds AI models for protein therapeutic design, trained on proprietary experimental data generated at unprecedented scale
Job Summary
Manifold Bio builds AI models for protein therapeutic design, trained on proprietary experimental data generated at unprecedented scale.
You will define and execute the strategic vision for our oligonucleotide therapeutic capabilities, leveraging our proprietary shuttle screening technology to discover and develop the next generation of tissue-targeted oligonucleotide therapeutics.
This role combines technical leadership of scientific staff focused on designing, screening, and evaluating tissue-targeted oligonucleotides, with strategic leadership of cross-functional drug discovery teams advancing lead molecules toward clinical testing.
Matching Summary
Manifold Bio builds AI models for protein therapeutic design, trained on proprietary experimental data generated at unprecedented scale.
Skills & Requirements
Must-have
Shuttled oligonucleotide therapeutics
Tissue-targeted oligonucleotide therapeutics
AI models for protein therapeutic design
High-throughput protein engineering
Computational design of biologics
Nice-to-have
Strategic scientific leader
Building complex technical platforms
Data-driven decisions
Dynamic biotech environment
Key Requirements
PhD in a relevant field
Minimum of 10 years post-PhD experience
Experience in industry drug-discovery programs
Diverse experience with multiple oligonucleotide modalities
Knowledge of delivery technologies for oligo medicines
Experience progressing oligonucleotide therapies from discovery through IND-enabling activities