Principal Scientist, Oligonucleotide Analytical Chemistry
GSK
Cambridge, MA, US
Base: $111,375 to $185,625; bonus/equity: annual b...
High-resolution lc/ms(-ms) methodology experience
Oligonucleotide or biopolymer mass spectrometry analysis
Analytical method development and troubleshooting
This role involves developing robust analytical methods to support GSK's pre-clinical oligonucleotide synthesis and novel chemistries
Job Summary
This role involves developing robust analytical methods to support GSK's pre-clinical oligonucleotide synthesis and novel chemistries.
The successful candidate will utilize advanced LC/MS-MS capabilities to characterize synthetic oligonucleotides in both low-and high-throughput settings.
GSK offers a competitive salary range, annual bonus eligibility, share-based long-term incentives, and comprehensive health and retirement benefits.
Matching Summary
This role involves developing robust analytical methods to support GSK's pre-clinical oligonucleotide synthesis and novel chemistries.
Salary
Base: $111,375 to $185,625; Bonus/Equity: Annual bonus and share-based long term incentive program; Benefits: Health care, retirement, paid holidays, vacation, and parental leave
Skills & Requirements
Must-have
High-resolution LC/MS(-MS) methodology experience
Oligonucleotide or biopolymer mass spectrometry analysis
Analytical method development and troubleshooting
BS degree with 8 years or MS with 6 years experience
Nice-to-have
PhD in analytical chemistry preferred
Experience with high-throughput data acquisition
Knowledge of NMR, X-ray crystallography, or CD spectroscopy
Cross-functional collaboration in drug discovery teams
Key Requirements
BS degree plus 8 years relevant experience OR MS degree plus 6 years
Minimum 2 years experience with high-resolution LC/MS(-MS)
At least 1 year experience in modern mass spec data analysis for biopolymers