Experience with protacs, adcs, and oligonucleotides
This role involves collaborating with preclinical R&D partners to drive compound design from target identification to clinical candidate selection
Job Summary
This role involves collaborating with preclinical R&D partners to drive compound design from target identification to clinical candidate selection.
The successful applicant will apply advanced computational strategies including AI/ML, de novo design, and multi-objective optimization to develop transformational medicines.
GSK aims to positively impact the health of 2.5 billion people by uniting science, technology, and talent to get ahead of disease together.
Matching Summary
This role involves collaborating with preclinical R&D partners to drive compound design from target identification to clinical candidate selection.
Skills & Requirements
Must-have
PhD in Computational Chemistry or related field
Expertise in AI/ML and QSAR modeling
Experience with PROTACs, ADCs, and oligonucleotides
Proficiency in Python scripting and Linux environments
Structure-based and ligand-based drug design skills
Nice-to-have
Post-doctoral research experience
Knowledge of toxicology and DMPK data analysis
Ability to present data in team meetings
Experience with protein structure prediction tools
Strong interpersonal skills in matrix teams
Key Requirements
PhD in Computational Chemistry, Cheminformatics, Physics, Biophysics, or Chemistry
Documented scientific contributions via publications or presentations
Location requirement: Collegeville, PA (2-3 days on-site)