Manager, Genetic Product Quality (fully Remote) — Variant Interpretation

Genomenoninc

Remote, United States
**
5+ years variant interpretation experience
Deep expertise in acmg/amp guidelines
Proficiency in hgvs nomenclature
** Genomenon, an AI-driven genetic intelligence company, is seeking a Manager of Genetic Product Quality (Variant Interpretation) to lead variant interpretation efforts in a fully remote position. The ideal candidate should have significant experience in variant interpretation, quality assurance, and team leadership, with a focus on improving systems and ensuring data accuracy for clinical applications. **

Job Summary

  • The role serves as the final scientific authority for complex variant interpretation cases involving conflicting clinical and functional evidence.
  • Candidates will lead a high-performing QA function to ensure consistency and scalability of variant interpretation efforts across global clients.
  • Genomenon combines AI with expert human curation to deliver clinically actionable datasets for rare diseases and cancer patients.

Matching Summary

Match Score: 75

** Genomenon, an AI-driven genetic intelligence company, is seeking a Manager of Genetic Product Quality (Variant Interpretation) to lead variant interpretation efforts in a fully remote position. The ideal candidate should have significant experience in variant interpretation, quality assurance, and team leadership, with a focus on improving systems and ensuring data accuracy for clinical applications. **

Skills & Requirements

Must-have

  • 5+ years variant interpretation experience
  • Deep expertise in ACMG/AMP guidelines
  • Proficiency in HGVS nomenclature
  • Clinical or equivalent setting experience
  • Advanced degree in Genetics or Genomics

Nice-to-have

  • Experience with ClinVar submissions
  • Prior people management experience
  • Experience developing SOPs
  • Broad range of disease areas exposure
  • Germline variant experience preferred

Key Requirements

  • PhD, MS in Genetics/Genomics or Genetic Counselor (CGC)
  • US-based remote work authorization required
  • Strong independent scientific decision-making capability

Work Rights

Must be US-based

Tailored Resume

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