Director Discovery Process And Analytical Development
AstraZeneca
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12+ years postgraduate industry experience
Lentiviral vector manufacturing expertise
Gmp and analytical development leadership
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AstraZeneca is seeking a Director of Discovery Process and Analytical Development to lead the strategy for early process development and analytical methods for novel in vivo lentiviral vectors. The successful candidate will drive innovation in cell and gene therapy, collaborating across teams to ensure compliance with regulatory standards and operational excellence.
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Job Summary
This role involves leading the strategy for adapting EsoBiotec's R&D vectors to bioreactor manufacturing and engineering new production cell lines.
The successful candidate will serve as a senior representative in cross-functional teams to shape comprehensive CMC strategies and ensure regulatory readiness.
You will direct vector manufacturing and quality testing at external CDMOs while establishing governance, oversight, and compliance frameworks.
Matching Summary
Match Score: 75
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AstraZeneca is seeking a Director of Discovery Process and Analytical Development to lead the strategy for early process development and analytical methods for novel in vivo lentiviral vectors. The successful candidate will drive innovation in cell and gene therapy, collaborating across teams to ensure compliance with regulatory standards and operational excellence.
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Skills & Requirements
Must-have
12+ years postgraduate industry experience
Lentiviral vector manufacturing expertise
GMP and analytical development leadership
CDMO oversight and management
CMC regulatory guideline fluency
Nice-to-have
Passion for gene therapy innovation
Strong stakeholder communication skills
Collaborative cross-functional mindset
Experience with in vivo cell therapies
Key Requirements
MSc or PhD in Virology, Biochemistry, Cell Biology, Molecular Biology, Biomedical Engineering, or related discipline
12+ years of postgraduate industry experience in manufacturing (including GMP) and analytical development
Proven track record leading process and analytical development teams
Familiarity with CMC regulatory guidelines for gene or cell therapy products