Principal Scientist - Medicinal Chemistry

Nurix Therapeutics

Houston, TX, United States
Base: $155,579 – $179,450; bonus/equity: included;...
On-site
Ph.d. in synthetic organic chemistry
8-10+ years pharmaceutical medicinal chemistry experience
Track record delivering advanced leads or development candidates
Nurix Therapeutics is seeking a Principal Scientist to design and synthesize novel degrader-based small molecules for treating cancer and inflammatory diseases

Job Summary

  • Nurix Therapeutics is seeking a Principal Scientist to design and synthesize novel degrader-based small molecules for treating cancer and inflammatory diseases.
  • The role requires a candidate with a Ph.D. in synthetic organic chemistry and over 8 years of industrial medicinal chemistry experience who can lead drug discovery programs from concept to phase transitions.
  • Candidates will collaborate with computational and structural biology groups while contributing to patent writing, scientific publications, and process improvements within the chemistry department.

Matching Summary

Nurix Therapeutics is seeking a Principal Scientist to design and synthesize novel degrader-based small molecules for treating cancer and inflammatory diseases.

Salary

Base: $155,579 – $179,450; Bonus/Equity: Included; Benefits: Not specified

Skills & Requirements

Must-have

  • Ph.D. in synthetic organic chemistry
  • 8-10+ years pharmaceutical medicinal chemistry experience
  • Track record delivering advanced leads or development candidates
  • Expertise in organic synthesis and structure-based drug discovery
  • Strong knowledge of ADME concepts and series SAR
  • Experience leading cross-functional project teams

Nice-to-have

  • Experience supervising direct reports and mentoring
  • Ability to function in a dynamic environment
  • Solutions and results-oriented focus
  • Hands-on approach with resourcefulness
  • Openness to diverse points of view

Key Requirements

  • Ph.D. in synthetic organic chemistry
  • 8-10+ years pharmaceutical medicinal chemistry industrial experience
  • Proven leadership capability in cross-functional teams
  • Strong synthetic problem-solving skills

Work Rights

Not specified

Tailored Resume

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