Senior Scientist, Protein And Structural Chemistry, Discovery Chemistry

Merck Sharp & Dohme Corp

Rahway, New Jersey, USA
Base: $117,000 - $184,200; bonus/equity: annual bo...
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Cryo-electron tomography (cryoet) expertise
X-ray crystallography or cryo-em experience
Sample preparation and data collection skills
** Merck Sharp & Dohme Corp is seeking a Senior Scientist in Protein and Structural Chemistry to join their Discovery Chemistry team in Rahway, New Jersey. The ideal candidate will possess expertise in cryo-electron tomography and complementary structural biology techniques, with a focus on collaboration and innovation in drug discovery. **

Job Summary

  • The role involves supporting protein structural determination from Discovery to Development across various therapeutic modalities.
  • Candidates will collaborate with cross-functional teams including medicinal chemists, informaticians, and biophysicists to drive drug design.
  • The position offers access to state-of-the-art instrumentation including Arctis FIB-SEM, Glacios, and Krios G4 microscopes.

Matching Summary

Match Score: 75

** Merck Sharp & Dohme Corp is seeking a Senior Scientist in Protein and Structural Chemistry to join their Discovery Chemistry team in Rahway, New Jersey. The ideal candidate will possess expertise in cryo-electron tomography and complementary structural biology techniques, with a focus on collaboration and innovation in drug discovery. **

Salary

Base: $117,000 - $184,200; Bonus/Equity: Annual bonus and long-term incentive eligible; Benefits: Medical, dental, vision, 401(k), paid holidays

Skills & Requirements

Must-have

  • Cryo-electron tomography (CryoET) expertise
  • X-ray crystallography or Cryo-EM experience
  • Sample preparation and data collection skills
  • Structure determination and analysis
  • Peer-reviewed publication capability

Nice-to-have

  • Cell culture on cryoEM grids
  • Tissue sample processing experience
  • Cryo-correlated light and electron microscopy
  • Gold labeling for cryoET samples
  • Protein complex structure determination

Key Requirements

  • Ph.D. in structural biology, biochemistry, or related field
  • Demonstrated experience in CryoET workflows
  • Experience in X-ray crystallography, Cryo-EM, or microED

Work Rights

Not specified

Sponsorship: available

Tailored Resume

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