Associate Principal Scientist – Downstream Vaccines And Advanced Biotechnologies Process R&d

Merck Sharp & Dohme Corp

West Point, Pennsylvania, United States
Base: $142,400.00 - $224,100.00; bonus/equity: ann...
Hybrid (3 days onsite, 1 day remote)
Downstream bioprocess development
Bioconjugation unit operations
Column chromatography experience
Merck Sharp & Dohme Corp is seeking an Associate Principal Scientist for their Downstream Vaccines and Advanced Biotechnologies Process R&D team in West Point, PA. The role focuses on leading bioconjugation process development for vaccine candidates, requiring a strong background in downstream bioprocessing and collaboration with cross-functional teams

Job Summary

  • The role involves leading downstream process design and development specifically for conjugate vaccine candidates within the Vaccine and Advanced Biotechnologies department.
  • Candidates will be responsible for de-risking later stage development by designing and executing process experiments to maximize production efficiency.
  • The position offers a comprehensive benefits package including medical, dental, vision, 401(k) retirement plans, and paid holidays alongside an annual bonus opportunity.

Matching Summary

Match Score: 85

Merck Sharp & Dohme Corp is seeking an Associate Principal Scientist for their Downstream Vaccines and Advanced Biotechnologies Process R&D team in West Point, PA. The role focuses on leading bioconjugation process development for vaccine candidates, requiring a strong background in downstream bioprocessing and collaboration with cross-functional teams.

Salary

Base: $142,400.00 - $224,100.00; Bonus/Equity: Annual bonus and long-term incentive eligible; Benefits: Medical, dental, vision, 401(k), paid holidays, vacation

Skills & Requirements

Must-have

  • Downstream bioprocess development
  • Bioconjugation unit operations
  • Column chromatography experience
  • Statistical design of experiments DOE
  • cGMP manufacturing understanding
  • Tangential and normal flow filtration

Nice-to-have

  • Antibody-drug conjugate experience
  • Team leadership and mentoring skills
  • CMC regulatory documentation authoring
  • Process technology transfer experience
  • Innovation in vaccine process development

Key Requirements

  • BS/MS/PhD in engineering or bio/chemical sciences
  • 5+ years hands-on laboratory experience in downstream bioprocess
  • 3-8 years pharmaceutical/biotech experience based on degree level
  • Strong understanding of scale-up principles

Work Rights

Not specified

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