Associate Principal Scientist, Immunology Cell Therapy Discovery

AstraZeneca

Base: $134,892.80 - $202,339.20; bonus/equity: eli...
Autoimmune and allergic disease biology
Computational biology/ai
In vitro assays and cell therapy research processes
The role centers on delivering scientific expertise for discovery initiatives with a dual focus on autoimmune / allergic disease biology (e.g., MS, IBD, asthma) and computational biology/AI

Job Summary

  • The role centers on delivering scientific expertise for discovery initiatives with a dual focus on autoimmune / allergic disease biology (e.g., MS, IBD, asthma) and computational biology/AI.
  • Lead the development of in vitro assays and cell therapy research processes to assess and validate novel therapeutic strategies and approaches.
  • Design and implement bioinformatics and AI/ML workflows for bulk and single-cell RNA sequencing, immune repertoire (TCR/BCR) analyses, multi-omics integration, target and pathway identification, biomarker and endotype discovery.

Matching Summary

The role centers on delivering scientific expertise for discovery initiatives with a dual focus on autoimmune / allergic disease biology (e.g., MS, IBD, asthma) and computational biology/AI.

Salary

Base: $134,892.80 - $202,339.20; Bonus/Equity: eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards; Benefits: qualified retirement programs, paid time off, health, dental, and vision coverage

Skills & Requirements

Must-have

  • autoimmune and allergic disease biology
  • computational biology/AI
  • in vitro assays and cell therapy research processes
  • bulk and single-cell RNA sequencing analysis
  • immune repertoire (TCR/BCR) analytics
  • multi-omics integration
  • target and pathway identification
  • biomarker and endotype discovery
  • programming skills in R and/or Python
  • workflow reproducibility
  • version control
  • data visualization
  • statistical modeling or machine learning
  • collaboration and communication capabilities

Nice-to-have

  • established industry network
  • peer-reviewed publications
  • experience across multiple therapeutic modalities

Key Requirements

  • PhD with 5+ years of relevant biotech/biopharma industry experience
  • Demonstrated proficiency in immunology assays
  • Demonstrated proficiency in computational biology/bioinformatics
  • Working knowledge of regulatory and quality considerations

Work Rights

Not specified

Tailored Resume

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