Head Of Computational Chemistry

General Proximity

San Francisco, CA, United States
On-site
Hands-on computational chemistry support
Structure-based and ligand-based design
Cheminformatics infrastructure development
General Proximity is a seed-stage startup developing induced proximity medicines (IPMs) to overcome therapeutic challenges unapproachable by other modalities

Job Summary

  • General Proximity is a seed-stage startup developing induced proximity medicines (IPMs) to overcome therapeutic challenges unapproachable by other modalities.
  • The successful candidate will serve as both a scientific leader and hands-on drug designer, guiding compound design from hit identification through candidate selection.
  • This role requires building a modern, AI-enabled computational platform from the ground up while remaining directly involved in molecule design.

Matching Summary

General Proximity is a seed-stage startup developing induced proximity medicines (IPMs) to overcome therapeutic challenges unapproachable by other modalities.

Skills & Requirements

Must-have

  • Hands-on computational chemistry support
  • Structure-based and ligand-based design
  • Cheminformatics infrastructure development
  • AI/ML molecular design tools implementation
  • SAR interpretation and optimization

Nice-to-have

  • Experience in seed-stage startup environment
  • Strong partnership with medicinal chemists
  • Ability to translate complex modeling results
  • Knowledge of AlphaFold-derived models
  • Familiarity with commercial computational tools

Key Requirements

  • Experience in pharma or biotech computational chemistry group
  • Deep technical expertise in molecular design
  • Practical medicinal chemistry judgment

Work Rights

Not specified

Tailored Resume

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