Senior Scientist, Lnp Platform & Process Development

Tr1x Inc

San Diego, CA, United States
Base: $145,000 - $160,000; bonus/equity: discretio...
On-site
Lnp formulation and process development
Mrna delivery systems
Analytical characterization of lnp
The Senior Scientist will lead the design, development, and optimization of lipid nanoparticle (LNP) formulation and process development efforts supporting the Tr1X in vivo CAR-Treg platform

Job Summary

  • The Senior Scientist will lead the design, development, and optimization of lipid nanoparticle (LNP) formulation and process development efforts supporting the Tr1X in vivo CAR-Treg platform.
  • Key responsibilities include contributing to LNP formulation design, developing scalable GMP-compatible manufacturing processes, and leading the development of analytical characterization methods.
  • Tr1X offers a competitive total rewards program including base salary, bonus, stock options, 401(k) with company contribution, health insurance, PTO, and paid holidays.

Matching Summary

The Senior Scientist will lead the design, development, and optimization of lipid nanoparticle (LNP) formulation and process development efforts supporting the Tr1X in vivo CAR-Treg platform.

Salary

Base: $145,000 - $160,000; Bonus/Equity: discretionary annual target bonus; incentive stock options; Benefits: 401(k) with company contribution; health and welfare insurance plans; PTO; paid holidays

Skills & Requirements

Must-have

  • LNP formulation and process development
  • mRNA delivery systems
  • analytical characterization of LNP
  • microfluidic or scalable mixing technologies
  • Quality by Design (QbD) principles
  • Design of Experiment (DoE) studies

Nice-to-have

  • immunotherapy or cell therapy platforms
  • correlating formulation attributes with in vivo performance
  • collaborate and develop relationships with CDMOs
  • mRNA production and analytical quality control

Key Requirements

  • Ph.D. with 4+ years industry experience or M.S. with 8+ years or B.S. with 10+ years
  • Hands-on experience with LNP formulation and process development
  • Experience with analytical characterization of LNP systems
  • Experience with mRNA therapeutics or nucleic acid delivery systems
  • Legally authorized to work for any employer in the U.S.

Work Rights

Legally authorized to work for any employer in the U.S.

Tailored Resume

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