Senior Scientist, Cellular Lead Profiling (automation)

Takeda UK

Boston, MA, US
Base: $137,000.00 - $215,270.00; bonus/equity: sho...
Ph.d. in cell biology or related field
High content assay (hca) development experience
Automated liquid handling system operation
The Senior Scientist will drive Takeda's Lab of the Future initiative by designing and executing cellular assays on fully automated, integrated platforms

Job Summary

  • The Senior Scientist will drive Takeda's Lab of the Future initiative by designing and executing cellular assays on fully automated, integrated platforms.
  • This role requires partnering with Drug Discovery Units, chemistry, and data sciences to translate complex cellular data into actionable insights for portfolio progression.
  • Candidates must ensure data quality and AI-readiness by applying advanced statistical methodologies to maintain reproducibility and reliability of decision-enabling datasets.

Matching Summary

The Senior Scientist will drive Takeda's Lab of the Future initiative by designing and executing cellular assays on fully automated, integrated platforms.

Salary

Base: $137,000.00 - $215,270.00; Bonus/Equity: Short-term and/or long-term incentives eligible; Benefits: Medical, dental, vision, 401(k) match, up to 120 hours vacation, tuition reimbursement

Skills & Requirements

Must-have

  • Ph.D. in Cell Biology or related field
  • High Content Assay (HCA) development experience
  • Automated liquid handling system operation
  • Assay miniaturization to 384/1536-well formats
  • Statistical analysis of Z' factor and curve-fit
  • Experience with GPCR and ion channel assays
  • Integration of LIMS/ELN systems

Nice-to-have

  • AI/ML integration into DMTA processes
  • Cross-functional collaboration skills
  • Mentoring junior scientific staff
  • Experience with CRISPR libraries
  • Strong data visualization capabilities

Key Requirements

  • Ph.D. with 2+ years industry experience OR M.S. with 8+ years OR B.S. with 10+ years
  • Hands-on experience with FLIPR and SyncroPatch 384PE platforms
  • Proven track record in hit-to-lead and lead optimization support
  • Working knowledge of Echo, Hamilton, Beckman, or Agilent liquid handlers

Work Rights

Not specified

Tailored Resume

Cover Letter