Principal Scientist, Vector Biology

Johnson & Johnson MedTech

Cambridge, Massachusetts, United States
$117,000.00 - $201,250.00 py
On-site
Viral entry biology
Cell-based assays
Lentiviral vector systems
Johnson & Johnson MedTech is seeking a Principal Scientist in Vector Biology to lead initiatives in receptor and viral entry biology. The role involves designing and validating cell-based assays, optimizing lentiviral transduction, and collaborating with cross-functional teams to drive therapeutic progress

Job Summary

  • Lead and contribute to research focused on the cellular and molecular mechanisms of enveloped virus entry.
  • Design, develop, and validate robust cell-based assays probing receptor expression/localization and ligand/virus binding, internalization/endocytosis pathways, and functional readouts.
  • Integrate data with cross-functional partners to inform target selection, vector design, and process improvements.

Matching Summary

Match Score: 85

Johnson & Johnson MedTech is seeking a Principal Scientist in Vector Biology to lead initiatives in receptor and viral entry biology. The role involves designing and validating cell-based assays, optimizing lentiviral transduction, and collaborating with cross-functional teams to drive therapeutic progress.

Salary

$117,000.00 - $201,250.00

Skills & Requirements

Must-have

  • viral entry biology
  • cell-based assays
  • lentiviral vector systems
  • mammalian cell culture
  • receptor-ligand interactions

Nice-to-have

  • pseudovirus or live-virus assays
  • high-throughput assay development
  • gene delivery platforms

Key Requirements

  • PhD in Cell Biology, Molecular Biology, Virology, Biochemistry, Biomedical Engineering or related field
  • 3-6 years of relevant industry experience
  • Proven track record developing quantitative cell-based assays
  • Direct experience with lentiviral vectors and transduction workflows

Work Rights

Not specified

Tailored Resume

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