Cmc Project Lead (next Generation Biologics And Adcs), London

Isomorphic Labs

London, United Kingdom
On-site
Biologics cmc
Antibody-drug conjugates (adcs)
Next-generation scaffolds
Drive the development and CMC strategy for our next-generation biologics and Antibody-Drug Conjugates (ADCs) pipeline

Job Summary

  • Drive the development and CMC strategy for our next-generation biologics and Antibody-Drug Conjugates (ADCs) pipeline.
  • Design and oversee end-to-end manufacturing frameworks for a diverse portfolio of novel scaffolds and functionalized antibodies.
  • Act as the primary author for CMC sections of global regulatory filings (IND/IMPD/BLA).

Matching Summary

Drive the development and CMC strategy for our next-generation biologics and Antibody-Drug Conjugates (ADCs) pipeline.

Skills & Requirements

Must-have

  • Biologics CMC
  • Antibody-Drug Conjugates (ADCs)
  • Next-generation scaffolds
  • cGMP and global regulatory guidelines
  • Analytical Target Profile definition
  • Global regulatory filings (IND/IMPD/BLA)

Nice-to-have

  • ML models for biologics design
  • AI tools to accelerate CMC processes

Key Requirements

  • PhD or MSc in Biochemistry, Chemical Engineering, Chemistry, or related
  • 8+ years of professional experience in biologics CMC
  • Direct, hands-on experience in ADC development, scale-up, or manufacturing
  • Deep knowledge of analytical techniques for multi-component molecules
  • Strong practical knowledge of cGMP and global regulatory guidelines

Work Rights

Not specified

Tailored Resume

Cover Letter