Principal Scientist, Chemical Biology - Discovery Chemistry

Johnson & Johnson UK

Beerse, Belgium
Onsite
Organic synthesis
Chemical biology expertise
Designing and synthesizing chemical biology tools
We are searching for an outstanding, highly skilled, and motivated chemist with excellent organic synthesis and chemical biology expertise to lead and manage our internal chemical biology efforts toward delivering high quality hits, leads, and candidates to Johnson & Johnson's discovery pipeline

Job Summary

  • We are searching for an outstanding, highly skilled, and motivated chemist with excellent organic synthesis and chemical biology expertise to lead and manage our internal chemical biology efforts toward delivering high quality hits, leads, and candidates to Johnson & Johnson's discovery pipeline.
  • The successful individual will be responsible for developing chemical probes and tool compounds to enable biological and mechanistic characterization of novel hits/hit series emerging from high-throughput screens and progressing them through stage-gates.
  • You will be responsible for driving and directing chemical biology functions for drug discovery projects, working in concert with partners in medicinal chemistry, chemoproteomics, disease area biology, and other key functions.

Matching Summary

We are searching for an outstanding, highly skilled, and motivated chemist with excellent organic synthesis and chemical biology expertise to lead and manage our internal chemical biology efforts toward delivering high quality hits, leads, and candidates to Johnson & Johnson's discovery pipeline.

Skills & Requirements

Must-have

  • organic synthesis
  • chemical biology expertise
  • designing and synthesizing chemical biology tools
  • activity-based protein profiling
  • photoaffinity labeling
  • cellular thermal shift assay

Nice-to-have

  • biopharmaceutical industry experience
  • targeted protein degradation strategies
  • scientific contributions
  • publication record
  • interdisciplinary work

Key Requirements

  • PhD in Organic Chemistry, Medicinal Chemistry, or Chemical Biology
  • 5+ years of post-PhD experience in Chemical Biology
  • Structure-Activity Relationship (SAR)-driven design and synthesis
  • chemical biology and chemoproteomics methods
  • chemical biology toward addressing target identification
  • peer-reviewed first-author publications
  • latest advances in synthetic chemistry and chemical biology

Work Rights

Not specified

Tailored Resume

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