Senior Scientist - Process Analytical Technology - Apicom
AstraZeneca
Dublin, Ireland
Competitive salary + benefits
Process analytical technology (pat)
Drug substance manufacturing
Pat spectroscopic techniques
This role will ensure the safe and timely introduction and manufacture of late-stage clinical and commercial API (Active Pharmaceutical Ingredients) in a state-of-the-art facility
Job Summary
This role will ensure the safe and timely introduction and manufacture of late-stage clinical and commercial API (Active Pharmaceutical Ingredients) in a state-of-the-art facility.
As an experienced Process Analytical Technology scientist, you will be responsible for leading the use of PAT as an enhanced control strategy solution in a modern, state-of-the-art manufacturing facility.
We are proud to be a great place to work and have a culture that inspires innovation and collaboration.
Matching Summary
This role will ensure the safe and timely introduction and manufacture of late-stage clinical and commercial API (Active Pharmaceutical Ingredients) in a state-of-the-art facility.
Salary
Competitive salary and benefits
Skills & Requirements
Must-have
Process Analytical Technology (PAT)
drug substance manufacturing
PAT spectroscopic techniques
chemometrics
cGMP for drug substance manufacturing
SHE principles
Nice-to-have
managing change in regulated manufacturing
developing multivariate models
coding in MATLAB or Python
Siemens SIPAT experience
technical supervision and mentoring
Key Requirements
Bachelors degree or PhD in chemistry, analytical chemistry or chemical engineering
Experience in R&D and/or Manufacturing
Proven record for PAT drug substance control strategies
Practical experience with major PAT spectroscopic techniques
Strong data-centric mindset and chemometrics ability