Principal Scientist, Computational Chemistry

Biogen

Base: $141,000.00-$188,000.00; bonus/equity: short...
Ph.d. in computational chemistry or related field
5+ years pharma/biotech experience
Deep expertise in structure based drug design
This role leverages advanced computational chemistry skills to support the design and prioritization of new small molecules for treating neurological and rare diseases

Job Summary

  • This role leverages advanced computational chemistry skills to support the design and prioritization of new small molecules for treating neurological and rare diseases.
  • The successful candidate will apply Free Energy Perturbation calculations and molecular dynamics simulations to guide medicinal chemistry optimization campaigns.
  • Biogen offers a competitive benefits package including up to $10,000 in tuition reimbursement, equity incentives, and a minimum of 15 days of paid vacation.

Matching Summary

This role leverages advanced computational chemistry skills to support the design and prioritization of new small molecules for treating neurological and rare diseases.

Salary

Base: $141,000.00-$188,000.00; Bonus/Equity: Short term and long-term incentives including cash bonus and equity; Benefits: Medical, Dental, Vision, Life, 401(k) match, Tuition reimbursement up to $10,000

Skills & Requirements

Must-have

  • Ph.D. in computational chemistry or related field
  • 5+ years pharma/biotech experience
  • Deep expertise in structure based drug design
  • Hands-on FEP workflow experience
  • Proficiency in molecular dynamics simulations
  • Experience with docking and ligand based modeling

Nice-to-have

  • Creative problem solving in team environment
  • Track record of scientific publications
  • Expertise with Schrödinger or MOE software
  • Python scripting proficiency
  • Ability to build automated workflows

Key Requirements

  • Ph.D. required
  • 5+ years pharmaceutical experience
  • Publication track record preferred

Work Rights

Not specified

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