Principal Scientist, Analytical Development, Oligo And Small Molecule
Praxis Precision Medicines
Remote, US
Remote
Oligonucleotide analytical method development
Small molecule gmp testing expertise
Cmc program leadership across cmos
The Principal Scientist will play a critical role in advancing the clinical and commercial pipeline by translating analytical strategies from development into manufacturing
Job Summary
The Principal Scientist will play a critical role in advancing the clinical and commercial pipeline by translating analytical strategies from development into manufacturing.
This role focuses on advancing oligonucleotide-based therapeutics while supporting small molecule programs with deep expertise in analytical method development and GMP testing.
The successful candidate will lead cross-functional partnerships to ensure robust, scalable, and compliant analytical control strategies for innovative CNS therapies.
Matching Summary
The Principal Scientist will play a critical role in advancing the clinical and commercial pipeline by translating analytical strategies from development into manufacturing.
Skills & Requirements
Must-have
Oligonucleotide analytical method development
Small molecule GMP testing expertise
CMC program leadership across CMOs
Analytical validation and qualification
Phase-appropriate control strategy design
Nice-to-have
Cross-functional collaboration skills
Agile analytical function development
CNS therapy experience
Technical troubleshooting capabilities
Key Requirements
Deep expertise in oligonucleotide drug substance analysis
Experience managing external CRO/CMO partners
Knowledge of regulatory documentation and specifications