Scientist – In Vitro Cancer Biology

RayzeBio

San Diego, CA, United States
Base: $118,259 - $143,302; bonus/equity: + incenti...
On-site
Design and optimize in vitro assays
Cell-based assays
Biochemical assays
Design, develop, and optimize in vitro and biochemical assays to answer challenging scientific questions and to support target validation, compound screening and mechanism of action studies for various pipeline projects

Job Summary

  • Design, develop, and optimize in vitro and biochemical assays to answer challenging scientific questions and to support target validation, compound screening and mechanism of action studies for various pipeline projects.
  • Apply rigorous equilibrium and kinetic binding models to extract quantitative parameters (Kd, Ki, kon, koff, residence time, stoichiometry) from radiometric and fluorescence-based platforms.
  • Safely work with radioactive isotopes in accordance with laboratory and regulatory guidelines.

Matching Summary

Design, develop, and optimize in vitro and biochemical assays to answer challenging scientific questions and to support target validation, compound screening and mechanism of action studies for various pipeline projects.

Salary

Base: $118,259 - $143,302; Bonus/Equity: Additional incentive cash and stock opportunities may be available; Benefits: Health Coverage, Wellbeing Support, Financial Well-being and Protection, Work-life benefits

Skills & Requirements

Must-have

  • design and optimize in vitro assays
  • cell-based assays
  • biochemical assays
  • quantitative characterization of drug-target interactions
  • radiometric and fluorescence-based platforms
  • work with radioactive isotopes
  • rigorous documentation of assay development

Nice-to-have

  • innovative critical thinker
  • technical problem solver
  • interdisciplinary drug discovery teams
  • strong publication record
  • AI tools for productivity

Key Requirements

  • Ph.D. degree in Cancer Biology, Cellular and Molecular Biology, or related field
  • Prior experience in drug discovery
  • Proficiency with cell culture
  • Proficiency with molecular biology techniques
  • Proficiency with ELISA
  • Proficiency with flow-cytometry
  • Proficiency with western blot
  • Proficiency with TR-FRET/HTRF
  • Proficiency with fluorescence-based competitive binding
  • Proficiency with high-content imaging
  • Ability to work with radioisotopes

Work Rights

Not specified

Tailored Resume

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