Associate Director, Quantitative Systems Pharmacology

GlaxoSmithKline

Cambridge, MA, US
Base: $151,500 to $252,500; bonus/equity: annual b...
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Phd in applied mathematics or related field
Experience with odes and parameter estimation
Proficiency in matlab, r, julia, or simbiology
** GlaxoSmithKline is seeking an Associate Director of Quantitative Systems Pharmacology to develop and apply QSP models that guide clinical study designs and interpret study results across various therapeutic areas, particularly in oncology. The ideal candidate will possess a PhD in a relevant field and have extensive experience in mathematical modeling, simulation, and quantitative pharmacology. **

Job Summary

  • This role involves building and utilizing QSP models to evaluate disease pathways and drug candidates within the oncology therapeutic area.
  • The successful candidate will serve as a point-of-contact for QSP modeling on project teams to solve challenging problems in drug research and development.
  • GSK offers a competitive salary range, annual bonus eligibility, share-based long-term incentives, and comprehensive health and retirement benefits.

Matching Summary

Match Score: 75

** GlaxoSmithKline is seeking an Associate Director of Quantitative Systems Pharmacology to develop and apply QSP models that guide clinical study designs and interpret study results across various therapeutic areas, particularly in oncology. The ideal candidate will possess a PhD in a relevant field and have extensive experience in mathematical modeling, simulation, and quantitative pharmacology. **

Salary

Base: $151,500 to $252,500; Bonus/Equity: Annual bonus and share-based long term incentive program; Benefits: Health care, retirement, paid holidays, vacation, and parental leave

Skills & Requirements

Must-have

  • PhD in Applied Mathematics or related field
  • Experience with ODEs and parameter estimation
  • Proficiency in MATLAB, R, Julia, or SimBiology
  • Experience with NONMEM, SAS, or WinNonlin
  • Mechanistically-sound PK-PD modeling experience

Nice-to-have

  • Familiarity with oncology drug development practices
  • Knowledge of mathematical modeling guidelines
  • Collaborative work in multidisciplinary teams
  • Experience integrating human genetics data
  • Passion for advancing patient care through science

Key Requirements

  • PhD in Applied Mathematics, Engineering, Pharmaceutical Sciences, or Systems Biology
  • Experience with numerical methods and statistical aspects of mathematical modeling
  • Computational experience with modeling packages like MATLAB, R, or C/C++

Work Rights

Not specified

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