Senior Scientist, Protein Sciences

pfizer.hu

Base: $93,600.00 to $156,000.00; bonus/equity: 12....
Protein expression and purification
Integral membrane protein reconstitution
Akta purification systems
You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries to generate tools to advance the Pfizer Portfolio of difficult targets

Job Summary

  • You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries to generate tools to advance the Pfizer Portfolio of difficult targets.
  • Represent Protein Sciences at the project team level, helping to guide new targets from gene through screening and beyond.
  • We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments.

Matching Summary

You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries to generate tools to advance the Pfizer Portfolio of difficult targets.

Salary

Base: $93,600.00 to $156,000.00; Bonus/Equity: 12.5% bonus target and share-based long-term incentive; Benefits: Comprehensive benefits package including 401(k), paid time off, medical, dental, and vision coverage.

Skills & Requirements

Must-have

  • protein expression and purification
  • integral membrane protein reconstitution
  • Akta purification systems
  • protein chemistry and analytics
  • design constructs for expression

Nice-to-have

  • analyze and understand protein structures
  • phage, yeast, or mRNA library generation
  • protein design using modern methods
  • establish binding approaches
  • scientific programming or data analysis

Key Requirements

  • PhD in Biochemistry, Structural Biology, or related discipline with 1-2 years experience
  • M.S. with 7+ years relevant experience including industry experience
  • Characterization of proteins by analytical and biophysical methods
  • Experience in expression construct design
  • Demonstrated ability to purify proteins
  • Experience in integral membrane protein reconstitution
  • Experience using Akta purification systems
  • Strong hands-on understanding of protein chemistry
  • Demonstrated ability to obtain results independently
  • Self-motivated, organized, and capable of working independently
  • Strong oral and written communication skills

Work Rights

Permanent work authorization in the United States

Tailored Resume

Cover Letter