Senior Scientist - Cell Culture Lead

Roche UK

Unknown, Unknown, United Kingdom
Cell line development strategy
Cell culture process development
Mammalian cell culture scale-up
Develop cell line development and cell culture process development strategy as a part of overall project technical development strategy to support IND and early clinical development

Job Summary

  • Develop cell line development and cell culture process development strategy as a part of overall project technical development strategy to support IND and early clinical development.
  • Drive cell line development and cell culture process development activities in collaboration with Roche TDTs and Roche qualified CDMO partners, including development and scale-up of mammalian cell culture and harvest process, from seed train to bioreactor harvest for production of biologics, lead clone selection, and process optimization.
  • At Roche you can show up as yourself, embraced for the unique qualities you bring.

Matching Summary

Develop cell line development and cell culture process development strategy as a part of overall project technical development strategy to support IND and early clinical development.

Skills & Requirements

Must-have

  • Cell line development strategy
  • Cell culture process development
  • Mammalian cell culture scale-up
  • cGMP compliance
  • ICH guidelines
  • Biologics CMC development

Nice-to-have

  • N-glycosylation adjustment
  • Pharmacopoeia familiarity
  • Open dialogue culture
  • Genuine connections

Key Requirements

  • Ph.D. or MS with 5+ years of CLD/CCPD experience
  • 5+ years of CLD and/or CCPD experience
  • 8+ years of relevant experience (MS degree)
  • Experience in biotech or pharma setting

Work Rights

Not specified

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