Associate Principal Scientist – Purification Scientist

Merck & Co., Inc.

Rahway, NJ, USA
Base: $142,400.00 - $224,100.00; bonus/equity: ann...
Hybrid
Hplc/uplc method development
Protein a affinity capture chromatography
Ion exchange (cex/aex) chromatography
The role involves developing innovative separation, analysis, and characterization strategies to accelerate the development of new medicines and vaccines

Job Summary

  • The role involves developing innovative separation, analysis, and characterization strategies to accelerate the development of new medicines and vaccines.
  • Candidates will partner with bioprocess and analytical scientists to deploy efficient bio/chemical isolation methods and deliver high purity materials.
  • The company offers a comprehensive benefits package including medical, dental, vision, 401(k), and an annual bonus eligibility.

Matching Summary

The role involves developing innovative separation, analysis, and characterization strategies to accelerate the development of new medicines and vaccines.

Salary

Base: $142,400.00 - $224,100.00; Bonus/Equity: Annual bonus and long-term incentive eligible; Benefits: Medical, dental, vision, 401(k), paid holidays, vacation

Skills & Requirements

Must-have

  • HPLC/UPLC method development
  • Protein A affinity capture chromatography
  • Ion exchange (CEX/AEX) chromatography
  • Size exclusion (SEC) chromatography
  • Hydrophobic interaction (HIC) chromatography
  • Reversed-phase chromatography
  • Drug-to-antibody ratio (DAR) analysis

Nice-to-have

  • Multidimensional separation techniques (2DLC)
  • Intact and subunit LC-MS structural characterization
  • Peptide mapping and glycan profiling
  • Deep appreciation of chemical structure interplay
  • Cross-functional team collaboration skills

Key Requirements

  • Ph.D. in biochemistry/chemistry or related field
  • 3-5 years experience in biopharmaceutical industry
  • M.S. with minimum 8 years experience option
  • Hands-on experience with mAb and ADC purification
  • Experience with LC-MS and orthogonal characterization techniques

Work Rights

Not specified

Tailored Resume

Cover Letter