Director, Computer System Compliance

beonemedicines.nl

Base: $172,500.00 - $232,500.00 annually; bonus/eq...
Computer system validation csa methodologies
21 cfr part 11 and annex 11 compliance
Ai/ml system validation experience
This role serves as the technical expert and lead for driving changes in the CSV/CSA domain by moving from static compliance to dynamic risk-based assurance with a focus on AI-driven platforms

Job Summary

  • This role serves as the technical expert and lead for driving changes in the CSV/CSA domain by moving from static compliance to dynamic risk-based assurance with a focus on AI-driven platforms.
  • The position requires managing multiple computer system validation projects while ensuring all resource expenditures align with budgets and providing input to Software Development Lifecycle processes.
  • BeOne Medicines offers a comprehensive benefits package including medical, dental, vision, 401(k), life insurance, paid time off, and opportunities for discretionary equity awards.

Matching Summary

This role serves as the technical expert and lead for driving changes in the CSV/CSA domain by moving from static compliance to dynamic risk-based assurance with a focus on AI-driven platforms.

Salary

Base: $172,500.00 - $232,500.00 annually; Bonus/Equity: Eligible for annual bonus plan and discretionary equity awards; Benefits: Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, Wellness

Skills & Requirements

Must-have

  • Computer System Validation CSA methodologies
  • 21 CFR Part 11 and Annex 11 compliance
  • AI/ML system validation experience
  • GAMP 5 (2nd Edition) expertise
  • Cloud platform validation AWS Azure GCP
  • Internal audit management and execution
  • Cross-functional team leadership

Nice-to-have

  • Generative AI and LLM risk assessment
  • Continuous Validation loop implementation
  • Agile and Waterfall project approaches
  • Automated testing tool proficiency
  • Python R or SQL data auditing skills
  • Global regulatory body inspection experience
  • Collaborative spirit and bold ingenuity

Key Requirements

  • Bachelor's degree required
  • 10+ years in Quality Assurance Compliance
  • 7+ years in software lifecycle methodologies
  • 5+ years validation systems using CSA
  • Experience with FDA MHRA Health Canada EMA inspections
  • Expert knowledge of GAMP 5 and 21 CFR Part 11

Work Rights

Not specified

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