Sr. Principal Scientist, Oncology Translational Research, Prostate

Johnson & Johnson UK

Spring House, Pennsylvania, United States of America
Base: $137,000 - $235,750; bonus/equity: not speci...
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Translational research and biomarker strategy
Prostate cancer drug development
Biomarker strategies for clinical trials
** Johnson & Johnson is seeking a Senior Principal Scientist for Oncology Translational Research specializing in prostate cancer. The role focuses on leading biomarker strategies and translational science efforts across clinical development programs, requiring a strong background in oncology and project leadership. **

Job Summary

  • This role will drive the design, implementation, and interpretation of biomarker strategies supporting early and late-stage clinical trials, including both registrational and exploratory studies.
  • The candidate will partner closely with clinical development, biostatistics, diagnostics, regulatory, discovery research, and external academic collaborators to translate biological insights into actionable clinical strategies.
  • Prepare and present translational and biomarker findings to internal governance committees and cross-functional teams, and represent the company at major scientific conferences.

Matching Summary

Match Score: 75

** Johnson & Johnson is seeking a Senior Principal Scientist for Oncology Translational Research specializing in prostate cancer. The role focuses on leading biomarker strategies and translational science efforts across clinical development programs, requiring a strong background in oncology and project leadership. **

Salary

Base: $137,000 - $235,750; Bonus/Equity: Not specified; Benefits: Medical, dental, vision, life insurance, disability, retirement plan, savings plan, long-term incentive program, vacation, sick time, holiday pay, work/personal/family time, parental leave, condolence leave, caregiver leave, volunteer leave, military spouse time-off

Skills & Requirements

Must-have

  • Translational research and biomarker strategy
  • Prostate cancer drug development
  • Biomarker strategies for clinical trials
  • Genomics and transcriptomics
  • Circulating biomarkers
  • Tissue-based molecular and spatial biomarkers
  • Immunologic and tumor microenvironment profiling
  • Digital pathology and computational biomarker approaches

Nice-to-have

  • Novel first in class RIPTACs
  • Data science and visualization tools
  • Prostate cancer biology expertise
  • Experience with PROTACs, RIPTACs
  • Expertise in immunology
  • Experience with circulating biomarkers
  • Familiarity with tissue-based biomarkers

Key Requirements

  • PhD in biomedical sciences
  • Postdoctoral training in a relevant biomedical field
  • Minimum 3 years after postdoc of biopharmaceutical drug development experience
  • Experience designing and implementing biomarker strategies in clinical trials
  • Strong background in translational oncology and biomarker science
  • Demonstrated ability to operate effectively in matrixed cross-functional teams
  • Excellent scientific communication, writing, and presentation skills
  • Strong organizational and project management capabilities

Work Rights

Not specified

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