The Vaccines and Advanced Biotechnologies (VAX) Process R&D team is responsible for the development and clinical manufacturing of Drug Substance and Drug Product Intermediates for the vaccine and advanced therapy pipeline
Job Summary
The Vaccines and Advanced Biotechnologies (VAX) Process R&D team is responsible for the development and clinical manufacturing of Drug Substance and Drug Product Intermediates for the vaccine and advanced therapy pipeline.
The Associate Principal Scientist will lead early downstream process design and development for recombinant subunit and/or conjugate vaccine products, contributing to new principles and methods for rapid early process development.
The role requires scientific/technical leadership, collaboration with cross-functional teams, and the ability to communicate results effectively in verbal and written formats.
Matching Summary
The Vaccines and Advanced Biotechnologies (VAX) Process R&D team is responsible for the development and clinical manufacturing of Drug Substance and Drug Product Intermediates for the vaccine and advanced therapy pipeline.
Salary
$139,600.00 - $219,700.00; Bonus/Equity: Eligible for annual bonus and long-term incentive; Benefits: Comprehensive package including medical, dental, vision, retirement, paid holidays, vacation, sick days
Skills & Requirements
Must-have
Downstream process design and development
Recombinant protein purification
Biomolecule conjugation techniques
Column chromatography and filtration
cGMP manufacturing understanding
Cross-functional team collaboration
Nice-to-have
Mentoring junior staff
Process and technology transfer
Authoring regulatory documentation
Flexibility in changing priorities
Willingness to work with infectious agents
Key Requirements
BS/MS/PhD with 7/5/3 years of experience
5+ years hands-on downstream process optimization
Experience with statistical design of experiments (DOE)
Strong understanding of large molecule purification unit operations