Associate Principal Scientist, Adjuvant Cmc Sme

AstraZeneca

Gaithersburg, MD, US
Base: $138,393 to $207,589; bonus/equity: short-te...
Hybrid
Vaccine adjuvant systems expertise
Mrna-lnp and vlp formulation experience
Gmp manufacturing and tech transfer
AstraZeneca is seeking an Associate Principal Scientist specializing in adjuvant CMC (Chemistry, Manufacturing, and Controls) to join their Vaccines Drug Product Development team. The successful candidate will lead formulation development for multi-antigen/adjuvant products and will be responsible for managing GMP operations and cross-functional collaboration

Job Summary

  • This role involves independently designing and developing formulations and drug product processes spanning Phase 1 through pivotal clinical development for next-generation preventative therapies.
  • The successful candidate will drive development strategies, manage external partners, and connect near-term deliverables to long-term patient impact within the Vaccines Drug Product Development team.
  • The position offers eligibility for short-term incentive bonuses, equity-based awards, and comprehensive health, dental, and vision coverage with a base salary ranging from $138,393 to $207,589.

Matching Summary

Match Score: 85

AstraZeneca is seeking an Associate Principal Scientist specializing in adjuvant CMC (Chemistry, Manufacturing, and Controls) to join their Vaccines Drug Product Development team. The successful candidate will lead formulation development for multi-antigen/adjuvant products and will be responsible for managing GMP operations and cross-functional collaboration.

Salary

Base: $138,393 to $207,589; Bonus/Equity: Short-term incentives and equity-based awards available; Benefits: Qualified retirement programs, paid time off, health, dental, and vision coverage

Skills & Requirements

Must-have

  • Vaccine adjuvant systems expertise
  • mRNA-LNP and VLP formulation experience
  • GMP manufacturing and tech transfer
  • IND/BLA/MAA CMC section authoring
  • Multi-antigen co-formulation development

Nice-to-have

  • Cross-functional leadership skills
  • Health authority interaction experience
  • Analytical strategy interface knowledge
  • Proactive risk anticipation
  • Patient impact focus

Key Requirements

  • BS/MS/PhD in Chemistry, Pharmaceutics, or related field
  • 5-10+ years in biopharmaceutical or vaccine development
  • Demonstrated expertise in aluminum and lipid-based adjuvants
  • Hands-on experience with mRNA-LNPs, bioconjugates, or VLPs
  • Proven track record in GMP manufacturing and tech transfer

Work Rights

Not specified

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