Director Vector Engineering

AstraZeneca

Boston, MA, United States
Base: $183,769 - $275,653 usd annual; bonus/equity...
Lentiviral vector therapeutic platform
Viral vector engineering expertise
Gene editing, car/tcr t cell engineering
Lead hypothesis-driven vector engineering from concept to preclinical candidate selection, including envelope/pseudotype, regulatory element, payload design, and transduction specificity

Job Summary

  • Lead hypothesis-driven vector engineering from concept to preclinical candidate selection, including envelope/pseudotype, regulatory element, payload design, and transduction specificity.
  • Build and scale in vitro and in vivo screening platforms and assays to characterize potency and safety, with robust data workflows.
  • Recruit, mentor, and develop discovery scientists while building a culture of scientific excellence, product focus, urgency, and accountability.

Matching Summary

Lead hypothesis-driven vector engineering from concept to preclinical candidate selection, including envelope/pseudotype, regulatory element, payload design, and transduction specificity.

Salary

Base: $183,769 - $275,653 USD Annual; Bonus/Equity: Short-term incentive bonus opportunity, equity-based long-term incentive program; Benefits: 401(k) plan, paid vacation and holidays, paid leaves, medical, prescription drug, dental, and vision coverage

Skills & Requirements

Must-have

  • Lentiviral vector therapeutic platform
  • Viral vector engineering expertise
  • Gene editing, CAR/TCR T cell engineering
  • Myeloid immunobiology in cancer
  • Hypothesis-driven vector engineering
  • In vitro and in vivo screening platforms

Nice-to-have

  • Culture of creativity and breakthroughs
  • Scientific passion driving impact
  • Bold thinking and inspiring medicines
  • Product-focused, decisive, rigorous mindset
  • Comfort operating in ambiguity

Key Requirements

  • PhD in molecular biology, virology, bioengineering, or related field
  • 12+ years of industry experience
  • Demonstrated track record designing viral vectors
  • Experience managing small to medium teams
  • Fluency with statistical design and analysis

Work Rights

Not specified

Tailored Resume

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