Executive Director, Cmc

Centessa Pharmaceuticals plc

Remote
Base: $285,000 - $370,000; bonus/equity: discretio...
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Small molecule drug development
Outsourced manufacturing partnerships
End-to-end cmc strategy
** Centessa Pharmaceuticals is seeking an Executive Director of CMC to lead small molecule development programs, focusing on strategy, operational oversight, and regulatory affairs. The ideal candidate should possess deep experience in small molecule drug development, excel in cross-functional collaboration, and thrive in a dynamic biotech environment. **

Job Summary

  • This high-impact leadership role requires a blend of scientific expertise, operational savvy, business acumen, technical efficiency, and strategic foresight.
  • The Executive Director, CMC will report directly to the SVP, CMC and will have ownership across the CMC function to include strategy, direct reports, team management, cross-functional leadership, and external manufacturing on our pipeline programs.
  • The annual base salary range for this job level is $285,000 - $370,000.

Matching Summary

Match Score: 75

** Centessa Pharmaceuticals is seeking an Executive Director of CMC to lead small molecule development programs, focusing on strategy, operational oversight, and regulatory affairs. The ideal candidate should possess deep experience in small molecule drug development, excel in cross-functional collaboration, and thrive in a dynamic biotech environment. **

Salary

Base: $285,000 - $370,000; Bonus/Equity: discretionary annual bonus and participation in equity program; Benefits: 401(k) plan, medical, dental, vision, life insurance, generous paid time off, health and wellness program

Skills & Requirements

Must-have

  • small molecule drug development
  • outsourced manufacturing partnerships
  • end-to-end CMC strategy
  • cGMP requirements
  • cross-functional collaboration

Nice-to-have

  • data driven decision making
  • asset-centric model
  • growth-stage biotech environment
  • scientific expertise
  • operational savvy

Key Requirements

  • Master’s degree in Organic Chemistry, Pharmaceutics, Chemical Engineering, or related scientific discipline (PhD preferred)
  • Minimum 15 years of pharmaceutical industry experience
  • at least 8 years in CMC
  • Strong track record in CMC leadership
  • Extensive experience working with CDMOs
  • In-depth knowledge of cGMP regulations
  • Demonstrated success in process development, scale-up, and validation
  • Prior experience drafting and submitting CMC content for regulatory filings

Work Rights

Not specified

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