Principal Scientist, Chemical Biology - Discovery Chemistry

Johnson & Johnson

Spring House, Pennsylvania, United States of America
Base: $117,000.00 - $201,250.00; bonus/equity: ann...
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Chemical biology expertise
Organic synthesis skills
Design and synthesis of chemical probes
** Johnson & Johnson is seeking a Principal Scientist in Chemical Biology within their Discovery Chemistry team, responsible for developing innovative drug candidates through collaborative research and development. The ideal candidate will have extensive experience in chemical biology and organic synthesis, with a strong emphasis on delivering high-quality chemical biology tools. **

Job Summary

  • Drive and direct chemical biology functions for drug discovery projects, working in concert with partners in medicinal chemistry, chemoproteomics, disease area biology, and other key functions.
  • Independently design and synthesize chemical biology tools, including photoaffinity and photocatalytic proximity labeling probes, and supervise synthetic chemistry activities at contract research organizations (CROs).
  • Forge a robust relationship with the Discovery Technologies & Molecular Pharmacology (DTMP) Chemoproteomics team to design, propose, and implement chem bio strategies and workstreams.

Matching Summary

Match Score: 75

** Johnson & Johnson is seeking a Principal Scientist in Chemical Biology within their Discovery Chemistry team, responsible for developing innovative drug candidates through collaborative research and development. The ideal candidate will have extensive experience in chemical biology and organic synthesis, with a strong emphasis on delivering high-quality chemical biology tools. **

Salary

Base: $117,000.00 - $201,250.00; Bonus/Equity: Annual performance bonus; Benefits: Medical, dental, vision, life insurance, disability, retirement plan, savings plan, paid time off

Skills & Requirements

Must-have

  • Chemical biology expertise
  • Organic synthesis skills
  • Design and synthesis of chemical probes
  • Photoaffinity and photocatalytic labeling probes
  • Structure-Activity Relationship (SAR)-driven design
  • Chemical biology and chemoproteomics methods

Nice-to-have

  • Biopharmaceutical industry experience
  • Targeted protein degradation strategies
  • Scientific contributions and publications
  • Collaboration with cross-functional teams

Key Requirements

  • PhD in Organic Chemistry, Medicinal Chemistry, or Chemical Biology
  • 5+ years post-PhD experience in Chemical Biology
  • Proven track record of delivering chemical biology probes
  • Demonstrated application of chemical biology toward target identification
  • Strong track record of scientific contributions
  • Ability to succeed within a matrix environment

Work Rights

Not specified

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