Director, Portfolio Strategy - Global Initiatives

Flagship Pioneering

Cambridge, United States
Base: $204,000 - $280,500; bonus/equity: annual in...
On-site
Biomedicines r&d portfolio
Strategy and business
Scientific rationale
This is a high-impact role at the intersection of science, strategy, and business, focused on shaping and advancing a differentiated BioMedicines R&D portfolio from early discovery through clinical development and commercialization readiness

Job Summary

  • This is a high-impact role at the intersection of science, strategy, and business, focused on shaping and advancing a differentiated BioMedicines R&D portfolio from early discovery through clinical development and commercialization readiness.
  • The role partners closely with senior BioMedicines and Flagship Pioneering leadership to define portfolio direction, build new R&D programs, and drive high-stakes investment and prioritization decisions.
  • Success in this role requires a roll-up-your-sleeves mindset—owning analyses, building materials, structuring decisions, and moving work forward in a fast-paced, ambiguity-rich environment.

Matching Summary

This is a high-impact role at the intersection of science, strategy, and business, focused on shaping and advancing a differentiated BioMedicines R&D portfolio from early discovery through clinical development and commercialization readiness.

Salary

Base: $204,000 - $280,500; Bonus/Equity: annual incentive program; Benefits: healthcare coverage, retirement benefits, broad range of other benefits

Skills & Requirements

Must-have

  • BioMedicines R&D portfolio
  • strategy and business
  • scientific rationale
  • development feasibility
  • execution risk
  • value creation
  • portfolio reviews
  • scenario planning
  • trade-off analyses
  • internal and external opportunities
  • scientific, technical, strategic, and operational diligence
  • portfolio risks, gaps, and opportunities
  • executive-level insights
  • senior scientific and executive leaders

Nice-to-have

  • roll-up-your-sleeves mindset
  • fast-paced, ambiguity-rich environment
  • deep science and structured problem-solving
  • influence without formal authority
  • Flagship ecosystem experience

Key Requirements

  • PhD or MD in Life Sciences or related field
  • 5+ years of experience in management consulting
  • biotech venture creation or investing
  • biopharma portfolio strategy
  • Strong understanding of biopharma R&D
  • clinical development, and regulatory pathways
  • Experience working across multiple programs
  • Demonstrated experience with portfolio construction
  • scenario planning, and risk-adjusted decision-making
  • Exceptional ability to synthesize complex data
  • communicate clearly with executives
  • Proven ability to influence senior leaders

Work Rights

Not specified

Tailored Resume

Cover Letter