Post Doctorate Scientist (ihb) - In Vitro Modeling Adaptive Immunologist

Roche Holding AG

Basel, Switzerland
Not specified (potentially hybrid or onsite based on company culture)
Ph.d. in immunology or related field completed within last 4 years
Deep expertise in adaptive immune biology t- and b-cell biology
Strong hands-on experience with flow cytometry and cell sorting
Roche Holding AG is seeking a Post Doctorate Scientist specializing in in vitro modeling of human adaptive immunity to work within their Institute of Human Biology in Basel, Switzerland. The ideal candidate will have expertise in human immunology and neuroinflammation, collaborating with computational scientists to develop experimental models that address conditions like multiple sclerosis and Alzheimer's disease

Job Summary

  • The role focuses on defining adaptive immune cell states in human CNS diseases like multiple sclerosis and Alzheimer's disease using in vitro modeling.
  • You will collaborate closely with computational scientists and drug developers to translate atlas-derived data into experimentally testable hypotheses.
  • Roche offers a highly collaborative open-lab environment where you can build experimental systems that directly interface with high-dimensional datasets.

Matching Summary

Match Score: 85

Roche Holding AG is seeking a Post Doctorate Scientist specializing in in vitro modeling of human adaptive immunity to work within their Institute of Human Biology in Basel, Switzerland. The ideal candidate will have expertise in human immunology and neuroinflammation, collaborating with computational scientists to develop experimental models that address conditions like multiple sclerosis and Alzheimer's disease.

Skills & Requirements

Must-have

  • Ph.D. in Immunology or related field completed within last 4 years
  • Deep expertise in adaptive immune biology T- and B-cell biology
  • Strong hands-on experience with flow cytometry and cell sorting
  • Experience working with primary human cells and tissue samples
  • Experience establishing in vitro model systems co-culture functional assays
  • Experience generating multi-omic datasets single-cell RNA-seq V(D)J profiling

Nice-to-have

  • Research experience in neuroinflammation multiple sclerosis or Alzheimer's disease
  • Familiarity with CNS and meningeal biology stromal cell interactions
  • Experience modeling tertiary lymphoid structures TLS or lymphoid organization
  • Experience with advanced in vitro systems organoids ex vivo tissue models
  • Experience with spatial biology workflows or sample preparation
  • Basic coding skills R or Python for computational collaboration

Key Requirements

  • Ph.D. degree required
  • Doctoral studies completed within the last four years
  • Professional fluency in English

Work Rights

Not specified

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