Director, Operational Excellence- Cell Therapy Manufacturing

AstraZeneca

Base: $148k - $222k annually; bonus/equity: eligib...
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Lean six sigma black belt certification
Gmp manufacturing experience in life sciences
Value stream mapping and hoshin deployment
** AstraZeneca is seeking a Director of Operational Excellence for its Cell Therapy Manufacturing division. This role focuses on improving operational efficiency through lean methodologies, overseeing value stream management, and ensuring compliance with manufacturing standards. **

Job Summary

  • The Director will lead the network-wide Operational Excellence agenda for AstraZeneca's autologous Cell Therapy division, focusing on eliminating waste across the entire vein-to-vein value stream.
  • This role requires applying the AZ Lean Model including A3 thinking, VSM, and standard work to deliver measurable outcomes in cost, productivity, service, quality, safety, and compliance.
  • Candidates must possess recognized Lean Six Sigma Black Belt status and over 10 years of experience in GMP manufacturing to effectively govern improvement portfolios and build sustainable capabilities for scale.

Matching Summary

Match Score: 75

** AstraZeneca is seeking a Director of Operational Excellence for its Cell Therapy Manufacturing division. This role focuses on improving operational efficiency through lean methodologies, overseeing value stream management, and ensuring compliance with manufacturing standards. **

Salary

Base: $148K - $222K annually; Bonus/Equity: Eligible for short-term incentives and equity-based awards; Benefits: Qualified retirement programs, paid time off, health, dental, and vision coverage

Skills & Requirements

Must-have

  • Lean Six Sigma Black Belt certification
  • GMP manufacturing experience in life sciences
  • Value stream mapping and Hoshin deployment
  • MES/EBR digital system expertise
  • Cross-site program leadership and governance

Nice-to-have

  • Advanced degree in engineering or life sciences
  • Experience with ATMP cGMP regulations
  • Strong influence without authority skills
  • Change leadership capabilities
  • Data integrity and GAMP knowledge

Key Requirements

  • Bachelor's degree in engineering or Life Sciences
  • 10+ years in GMP manufacturing
  • 5+ years leading programs
  • Lean Six Sigma Black Belt certification
  • Experience with MES/EBR/LIMS systems

Work Rights

Not specified

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