Pk/pd And Qsp Modeler, Neuroscience – Principal Scientist / Associate Scientist, Dmpk & Modeling
Takeda UK
Fujisawa, Japan
Quantitative mathematical models
Modeling and simulation strategy
Translational pk/pd/efficacy models
Drive decision-making in drug discovery and development by building a quantitative model of novel therapeutic agents to treat various neurological diseases including neurodegeneration and neuromuscular diseases
Job Summary
Drive decision-making in drug discovery and development by building a quantitative model of novel therapeutic agents to treat various neurological diseases including neurodegeneration and neuromuscular diseases.
Formulate and implement team-engaged right modeling & simulation strategy.
Enable translational predictions of human pharmacologically active/efficacious dose, dosing schedule and safety margin for clinical trials.
Matching Summary
Drive decision-making in drug discovery and development by building a quantitative model of novel therapeutic agents to treat various neurological diseases including neurodegeneration and neuromuscular diseases.
Skills & Requirements
Must-have
quantitative mathematical models
modeling and simulation strategy
translational PK/PD/efficacy models
biological systems mathematical modeling
complex information analysis
Nice-to-have
patient-focused innovation
global team collaboration
strong interest in neurological diseases
Key Requirements
MS/PhD/PharmD in relevant scientific field
Competency in MATLAB, SimBiology, NONMEM, Monolix, Phoenix, Python, or R
Experience in mathematical modeling of biological systems
Good English communication skill (TOEIC score ≥750)