Scientist, Oligo Discovery Biology (sequencing Assays)

GlaxoSmithKline

Massachusetts, United States
Base: $89,925 to $149,875; bonus/equity: annual bo...
Next-generation sequencing (ngs) assays
Rna-seq, amp-seq development
Nucleic acid extraction
Design, optimize, and execute next-generation sequencing (NGS) assays to characterize oligonucleotide activity, including on-target efficacy and transcriptome-wide off-target effects

Job Summary

  • Design, optimize, and execute next-generation sequencing (NGS) assays to characterize oligonucleotide activity, including on-target efficacy and transcriptome-wide off-target effects.
  • Collaborate effectively with team members and cross-functional partners in biology, chemistry, and bioinformatics to advance platform capabilities and portfolio projects.
  • Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

Matching Summary

Design, optimize, and execute next-generation sequencing (NGS) assays to characterize oligonucleotide activity, including on-target efficacy and transcriptome-wide off-target effects.

Salary

Base: $89,925 to $149,875; Bonus/Equity: annual bonus and eligibility for share-based long term incentive program; Benefits: health care, insurance, retirement, paid holidays, vacation, paid caregiver/parental and medical leave

Skills & Requirements

Must-have

  • Next-generation sequencing (NGS) assays
  • RNA-seq, Amp-Seq development
  • Nucleic acid extraction
  • NGS library preparation
  • Quantitative PCR methods
  • Drug discovery with oligonucleotide therapeutics

Nice-to-have

  • Sense of urgency, flexibility, independence
  • Accountability and high level of integrity
  • Team-based culture
  • Attention to detail
  • Basic command-line environment experience

Key Requirements

  • MS with 3+ years or BS with 5+ years experience
  • 2+ years NGS experience
  • Independently plan and execute experiments
  • Experience with NGS workflows including library prep
  • Experience with core molecular biology techniques
  • Experience with laboratory automation and liquid handlers

Work Rights

Not specified

Tailored Resume

Cover Letter