Senior Scientist, Protein Sciences

pfizer.dk

Base: $93,600.00 - $156,000.00; bonus/equity: 12.5...
Protein expression and purification
Integral membrane protein reconstitution
Protein quality control
You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries to generate tools to advance the Pfizer Portfolio of difficult targets including integral membrane proteins and their reconstitution in non-detergent formulations

Job Summary

  • You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries to generate tools to advance the Pfizer Portfolio of difficult targets including integral membrane proteins and their reconstitution in non-detergent formulations.
  • Represent Protein Sciences at the project team level, helping to guide new targets from gene through screening and beyond.
  • We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments.

Matching Summary

You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries to generate tools to advance the Pfizer Portfolio of difficult targets including integral membrane proteins and their reconstitution in non-detergent formulations.

Salary

Base: $93,600.00 - $156,000.00; Bonus/Equity: 12.5% bonus target, eligible for LTI; Benefits: Comprehensive benefits package

Skills & Requirements

Must-have

  • Protein expression and purification
  • Integral membrane protein reconstitution
  • Protein quality control
  • Akta purification systems
  • Protein chemistry and analytics

Nice-to-have

  • Protein structure analysis
  • Library generation and display selection
  • Protein design for stabilization
  • Binding approaches for molecules

Key Requirements

  • PhD in Biochemistry, Structural Biology, or related discipline with 1-2 years experience
  • M.S. with 7+ years relevant experience
  • Experience with analytical and biophysical methods
  • Experience in expression construct design
  • Experience purifying challenging proteins
  • Experience in integral membrane protein reconstitution
  • Permanent work authorization in the United States

Work Rights

Permanent work authorization required

Tailored Resume

Cover Letter