You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries
Job Summary
You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries.
With your deep knowledge of the discipline, you will be recognized as a technical expert and a scientific contributor who routinely partners with, and mentors junior colleagues within the department and across therapeutic areas.
The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program.
Matching Summary
You will be responsible for expression construct design and purification from bacterial, insect, and mammalian cells, protein quality control, as well as the generation and screening of mutant libraries.
Salary
Base: $93,600.00 - $156,000.00; Bonus/Equity: 12.5% bonus target; Benefits: Comprehensive benefits package including 401(k), paid time off, health benefits
Skills & Requirements
Must-have
Protein expression and purification
Integral membrane protein reconstitution
Protein quality control
Akta purification systems
Protein chemistry and analytics
Nice-to-have
Protein structure analysis
Phage, yeast, or mRNA library generation
Protein design for stabilization
Binding approaches for molecules
Key Requirements
PhD in Biochemistry, Structural Biology, or related discipline with 1-2 years experience
M.S. with 7+ years relevant experience including industry experience
Experience in protein expression and purification
Experience with analytical and biophysical methods
Experience in expression construct design
Experience purifying challenging proteins
Experience with integral membrane protein reconstitution