Thesis Work, 45 Credits - Generation And Optimization Of 3d Ipsc-derived Lung Alveolospheres For Assay Development

AstraZeneca

Gothenburg, Sweden
Ipsc-derived lung alveolospheres
Automation and design of experiments
Cell culture, imaging analysis, and qpcr
This project aims to develop and optimize culture conditions for iPSC-derived lung alveolospheres by leveraging automation and systematic design of experiments (DoE)

Job Summary

  • This project aims to develop and optimize culture conditions for iPSC-derived lung alveolospheres by leveraging automation and systematic design of experiments (DoE).
  • The optimized system will be validated by exposing alveolospheres to fibrotic and inflammatory stimuli, assessing model fidelity, robustness, and translational relevance.
  • Your work will help create advanced in vitro lung models applicable in disease mechanism studies and high-throughput screening for drug discovery.

Matching Summary

This project aims to develop and optimize culture conditions for iPSC-derived lung alveolospheres by leveraging automation and systematic design of experiments (DoE).

Skills & Requirements

Must-have

  • iPSC-derived lung alveolospheres
  • automation and design of experiments
  • cell culture, imaging analysis, and qPCR
  • robust and disease-relevant lung models
  • quality control frameworks

Nice-to-have

  • science-led, patient-centered
  • entrepreneurial spirit
  • meaningful projects
  • broad skillset and knowledge base

Key Requirements

  • Enrolled in a master's program
  • Experience with cell culture is essential
  • Experience with complex 3D models is preferred

Work Rights

Not specified

Tailored Resume

Cover Letter