Senior Scientist Ii/associate Principal Scientist, Pharmacology

AstraZeneca

Humanized mouse system experience
In vivo car-t study design
Flow cytometry panel design
You will lead in vivo pharmacology and immune monitoring to enable data-driven progression of cell therapy and immuno-oncology programs

Job Summary

  • You will lead in vivo pharmacology and immune monitoring to enable data-driven progression of cell therapy and immuno-oncology programs.
  • The role requires owning key humanized mouse platforms and associated workflows to deliver rigorous datasets for candidate selection and dose strategy.
  • Candidates must demonstrate strong flow cytometry competence and the ability to manage end-to-end study delivery with internal teams and external partners.

Matching Summary

You will lead in vivo pharmacology and immune monitoring to enable data-driven progression of cell therapy and immuno-oncology programs.

Skills & Requirements

Must-have

  • Humanized mouse system experience
  • In vivo CAR-T study design
  • Flow cytometry panel design
  • Oncology tumor microenvironment analysis
  • CRO and vendor management

Nice-to-have

  • Pipeline scaling experience
  • Immune profiling integration
  • Combination strategy support
  • Translational biomarker strategy

Key Requirements

  • PhD in Immunology, Pharmacology, or related field
  • Practical experience with humanized mouse systems
  • Strong understanding of CAR-T biology
  • Hands-on flow cytometry experience preferred

Work Rights

Not specified

Tailored Resume

Cover Letter