Principal Scientist/associate Director, Dmpk

Disc Medicine

Watertown, Massachusetts, United States
Base: $184,000 - $224,000 usd; bonus/equity: not s...
On-site
Expertise in large-molecule pk and pkpd
Design and interpretation of in vivo studies
Experience with adme and human pk projection
Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering novel treatments for serious hematologic diseases

Job Summary

  • Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering novel treatments for serious hematologic diseases.
  • The role involves applying in vitro, in vivo, and modeling approaches to characterize the absorption, distribution, metabolism, excretion, and PK/PD properties of drug candidates.
  • Candidates will serve as a DMPK project representative contributing across all stages from early compound screening through IND-enabling studies and regulatory submissions.

Matching Summary

Disc Medicine is a clinical-stage biopharmaceutical company committed to discovering novel treatments for serious hematologic diseases.

Salary

Base: $184,000 - $224,000 USD; Bonus/Equity: Not specified; Benefits: Comprehensive benefits package

Skills & Requirements

Must-have

  • Expertise in large-molecule PK and PKPD
  • Design and interpretation of in vivo studies
  • Experience with ADME and human PK projection
  • Overseeing external CRO partners
  • Cross-functional team collaboration

Nice-to-have

  • Strong knowledge of small molecule ADME
  • Innovative PK and PK/PD approaches
  • Strategic guidance for regulatory filings
  • Entrepreneurial spirit and drive for excellence

Key Requirements

  • MS in DMPK/biology/chemistry with 8+ years experience
  • PhD with 5+ years industry experience
  • Demonstrated expertise in large-molecule PK
  • Proven ability to predict human PK

Work Rights

Not specified

Tailored Resume

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