Postdoctoral Fellow – Next-gen 3d Bio-interfaces: Mapping The Cross-talk Between Tme And Peripheral Immunity

AstraZeneca

Gaithersburg, MD, USA
Base: $103,079 - $123,694; bonus/equity: short-ter...
3d ex vivo culture systems
Tumor immunobiology expertise
Immuno-oncology drug mechanisms
Research and develop next-generation experimental tools for dissecting the mechanisms of action for immuno-oncology drugs using multi-organ 3D ex vivo culture systems

Job Summary

  • Research and develop next-generation experimental tools for dissecting the mechanisms of action for immuno-oncology drugs using multi-organ 3D ex vivo culture systems.
  • Conduct pioneering research to better understand immune checkpoints and their modulators using patient-derived samples and cutting-edge technologies.
  • Develop laboratory methods to assess peripheral immune cell activation, recruitment to the tumor microenvironment, and subsequent anti-tumor immune responses.

Matching Summary

Research and develop next-generation experimental tools for dissecting the mechanisms of action for immuno-oncology drugs using multi-organ 3D ex vivo culture systems.

Salary

Base: $103,079 - $123,694; Bonus/Equity: short-term incentive; Benefits: Competitive Benefits Package

Skills & Requirements

Must-have

  • 3D ex vivo culture systems
  • Tumor immunobiology expertise
  • Immuno-oncology drug mechanisms
  • Single cell RNA sequencing
  • CODEX multiplexed tissue imaging
  • Peripheral immune cell activation

Nice-to-have

  • Patient-derived samples
  • Predictive models
  • Entrepreneurial spirit
  • Cross-functional collaboration

Key Requirements

  • PhD or DVM awarded within 4 years
  • Immunology knowledge and assays
  • Tissue specimen experience
  • 0-4 years of working experience

Work Rights

Not specified

Tailored Resume

Cover Letter