Associate Principal Scientist, Downstream Process Development

Merck & Co., Inc.

Base: $142,400.00 - $224,100.00; bonus/equity: ann...
Downstream purification process design
Chromatography and filtration expertise
Biologics cmc development cycle knowledge
The role involves designing and optimizing downstream unit operations such as cell harvest, filtration, and chromatography for early and late-stage biological products

Job Summary

  • The role involves designing and optimizing downstream unit operations such as cell harvest, filtration, and chromatography for early and late-stage biological products.
  • Candidates are expected to lead biologic downstream process development for first-in-human and commercial processes while ensuring high yield and scalability.
  • The position offers a comprehensive benefits package including medical, dental, vision, retirement plans, and eligibility for annual bonuses and long-term incentives.

Matching Summary

The role involves designing and optimizing downstream unit operations such as cell harvest, filtration, and chromatography for early and late-stage biological products.

Salary

Base: $142,400.00 - $224,100.00; Bonus/Equity: Annual bonus and long-term incentive eligible; Benefits: Medical, dental, vision, 401(k), paid holidays, vacation

Skills & Requirements

Must-have

  • Downstream purification process design
  • Chromatography and filtration expertise
  • Biologics CMC development cycle knowledge
  • Leading cross-functional project teams
  • Mentoring junior scientists

Nice-to-have

  • Data science and digital tool leverage
  • High throughput experimentation automation
  • Continuous processing technology experience
  • Predictive modeling and machine learning
  • External scientific publication track record

Key Requirements

  • Ph.D. with 3+ years industry experience or Master's with 6+ years
  • BS degree with 8+ years in Chemical/Biochemical Engineering
  • Proven record of accomplishments in downstream process development
  • Scientific understanding of recombinant protein purification principles
  • Ability to direct planning and execution of process development stages

Work Rights

Not specified

Sponsorship: available

Tailored Resume

Cover Letter