Associate Scientist Postdoctoral Fellow - Computational Precision Genetics

Merck Sharp & Dohme Corp

Cambridge, Massachusetts, USA
Hybrid (3 days on-site, 1 day remote)
Single-cell transcriptomics analysis
Spatial transcriptomics processing
Ai/ml model development for biomarkers
The Associate Scientist Postdoctoral Fellow position at Merck Sharp & Dohme Corp focuses on developing computational frameworks for identifying biomarkers in autoimmune diseases. The role emphasizes collaboration and innovation in a hybrid work environment, requiring expertise in computational biology, AI/ML, and multi-omics data analysis

Job Summary

  • The role involves developing a reusable multi-omics and AI/ML framework to discover mechanism-based companion diagnostic biomarkers for autoimmune diseases.
  • Candidates will analyze complex pre- and post-treatment readouts including single-cell RNA-seq, spatial transcriptomics, and cytokine profiling.
  • This position offers the opportunity to work within a best-in-industry Postdoctoral Research Fellow Program combining academic focus with commercial resources.

Matching Summary

Match Score: 85

The Associate Scientist Postdoctoral Fellow position at Merck Sharp & Dohme Corp focuses on developing computational frameworks for identifying biomarkers in autoimmune diseases. The role emphasizes collaboration and innovation in a hybrid work environment, requiring expertise in computational biology, AI/ML, and multi-omics data analysis.

Skills & Requirements

Must-have

  • Single-cell transcriptomics analysis
  • Spatial transcriptomics processing
  • AI/ML model development for biomarkers
  • Python or R programming skills
  • Multi-omic integration strategies

Nice-to-have

  • Organoid model data generation experience
  • Cloud platform (AWS) familiarity
  • High-performance computing environments
  • Translational biomarker discovery background
  • Genotype/SNP data integration experience

Key Requirements

  • Ph.D. in Computational Biology, Bioinformatics, or related field
  • Completion of Ph.D. within 6 months allowed
  • Proven experience with Seurat, Scanpy, or similar tools
  • Strong statistical skills for high-dimensional biological data

Work Rights

Not specified

Sponsorship: available

Tailored Resume

Cover Letter