Director, External Manufacturing - Viral Vectors

AstraZeneca

Gaithersburg, MD, US
Base: $180,740.80 - $271,111.20; bonus/equity: sho...
Not specified (assumed hybrid based on location flexibility).
Viral vector cdmo partnerships
External manufacturing network leadership
Gmp compliance at cdmos
AstraZeneca is seeking a Director of External Manufacturing for Viral Vectors to lead CDMO partnerships and ensure effective supply and technical robustness for their Cell Therapy portfolio. The ideal candidate should have extensive experience in viral vector CMC, external manufacturing management, and strong leadership skills

Job Summary

  • Lead end-to-end CDMO partnerships aligning external execution with AstraZeneca’s business objectives to deliver reliable, cost-effective supply and technical robustness across preclinical, clinical, and commercial stages.
  • Establish, manage, and continuously improve a regional and global portfolio of LVV and plasmid CDMO partners, aligning site capabilities with program needs and lifecycle stage.
  • Partner with QA to ensure GMP compliance at CDMOs, support audits, investigations, and CAPAs, and maintain alignment with global regulations and evolving guidance for viral vectors and plasmids.

Matching Summary

Match Score: 85

AstraZeneca is seeking a Director of External Manufacturing for Viral Vectors to lead CDMO partnerships and ensure effective supply and technical robustness for their Cell Therapy portfolio. The ideal candidate should have extensive experience in viral vector CMC, external manufacturing management, and strong leadership skills.

Salary

Base: $180,740.80 - $271,111.20; Bonus/Equity: short-term incentive bonus opportunity, equity-based long-term incentive program; Benefits: 401(k) plan, paid vacation and holidays, paid leaves, health benefits (medical, prescription drug, dental, vision)

Skills & Requirements

Must-have

  • Viral vector CDMO partnerships
  • External manufacturing network leadership
  • GMP compliance at CDMOs
  • Process development and tech transfer
  • Supply assurance and operations

Nice-to-have

  • Continuous improvement and innovation
  • Stakeholder engagement and alignment
  • Operational excellence and KPIs

Key Requirements

  • 10+ years in biopharmaceuticals
  • 5+ years managing external manufacturing/CDMOs
  • Advanced degree (PhD or MS preferred)
  • Proven track record of tech transfer and commercial readiness for viral vectors

Work Rights

Not specified

Tailored Resume

Cover Letter