Amgen Australia is seeking a Senior Principal Scientist in Chemical Biology and Proximity-based Therapeutics to lead discovery efforts in drug development. The role emphasizes the integration of chemical biology and phenotypic screening to uncover novel therapeutic opportunities, focusing on molecular glue discovery and disease-relevant models
Job Summary
This role leads discovery efforts at the intersection of chemical biology and induced proximity to address previously undruggable targets.
The successful candidate will integrate phenotypic findings with mechanistic biology to translate discoveries into drug discovery programs.
Amgen offers a comprehensive benefits package including retirement plans, health coverage, and stock-based long-term incentives.
Matching Summary
Match Score: 85
Amgen Australia is seeking a Senior Principal Scientist in Chemical Biology and Proximity-based Therapeutics to lead discovery efforts in drug development. The role emphasizes the integration of chemical biology and phenotypic screening to uncover novel therapeutic opportunities, focusing on molecular glue discovery and disease-relevant models.
Salary
Base: $162,509.80 - $219,866.20 USD; Bonus/Equity: Discretionary annual bonus and stock-based incentives; Benefits: Comprehensive health, dental, vision, and retirement plans
Skills & Requirements
Must-have
Phenotypic screening strategies
Chemical genetics approaches
Disease-relevant cellular models
High-content assay development
Mechanism-of-action studies
Nice-to-have
Omics data analysis expertise
Cross-functional team leadership
Proteomics or transcriptomics experience
Scientific publication record
Mentoring junior scientists
Key Requirements
Doctorate in Chemical Biology or related field
3+ years in small molecule discovery
Experience with proximity-based mechanisms
Master's degree with 6 years experience OR Bachelor's with 8 years