Senior Principal Ai/ml Cheminformatics Scientist

Pfizer

Multiple Locations
Base: $124,400.00 - $207,400.00; bonus/equity: 17....
Hybrid
Ai/ml cheminformatics for drug discovery
Develop and deploy ai workflows
Python with rdkit, openeye, deepchem
Pfizer is seeking a Senior Principal AI/ML Cheminformatics Scientist to join their computational absorption, distribution, metabolism, and excretion (cADME) group. The role involves developing AI-driven solutions for drug discovery, collaborating with interdisciplinary teams, and utilizing extensive chemical and biological data sets

Job Summary

  • Drive scientific and technical advancement in PDM’s AI and cheminformatics capabilities by developing and delivering robust, validated workflows and algorithms that directly support drug discovery.
  • Design, build, and deploy innovative cheminformatics and AI workflows for small molecule discovery, with clear deliverables including prioritized compound lists, well-defined chemical libraries, and actionable structure-activity relationship analyses.
  • Continuously monitor and evaluate emerging advances in AI, cheminformatics, and computational drug discovery, proactively leading the adoption of promising new methodologies.

Matching Summary

Match Score: 85

Pfizer is seeking a Senior Principal AI/ML Cheminformatics Scientist to join their computational absorption, distribution, metabolism, and excretion (cADME) group. The role involves developing AI-driven solutions for drug discovery, collaborating with interdisciplinary teams, and utilizing extensive chemical and biological data sets.

Salary

Base: $124,400.00 - $207,400.00; Bonus/Equity: 17.5% bonus target; Benefits: Comprehensive benefits package including 401(k), paid time off, medical, dental, vision

Skills & Requirements

Must-have

  • AI/ML cheminformatics for drug discovery
  • Develop and deploy AI workflows
  • Python with RDKit, OpenEye, DeepChem
  • Molecular representations and property prediction
  • Collaborate with medicinal chemists and biologists

Nice-to-have

  • Publication or presentation of results
  • Adoption of promising new methodologies
  • Experience with generative models and transformers

Key Requirements

  • Ph.D. or Master’s degree in Cheminformatics, Computational Chemistry, Bioinformatics, Data Science, or related field
  • 8+ years of experience in drug discovery
  • Experience with AI methods in medicinal chemistry/cheminformatics
  • Proficiency in Python and cheminformatics libraries
  • Experience with version control systems like Git

Work Rights

Must have permanent work authorization

Tailored Resume

Cover Letter