Senior Scientist Ii, Cell Therapy Discovery

AstraZeneca

Car design and t-cell engineering
In vitro functional characterization
Primary cell culture and maintenance
You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization

Job Summary

  • You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization.
  • You will partner with project teams to enable data-driven decisions that advance programs from discovery toward translation.
  • AstraZeneca embraces diversity and equality of opportunity and is committed to building an inclusive and diverse team.

Matching Summary

You will own key assays and workflows for CAR design, T-cell engineering, and in vitro functional characterization.

Skills & Requirements

Must-have

  • CAR design and T-cell engineering
  • in vitro functional characterization
  • Primary cell culture and maintenance
  • Lentiviral vector preparation and transduction
  • Flow cytometry panel design and gating
  • Functional assay development and execution
  • Molecular methods (PCR/qPCR, NGS prep)

Nice-to-have

  • Data-driven decision making
  • Cross-functional team collaboration
  • Mentoring junior colleagues
  • Troubleshooting experimental models
  • Experience with advanced CAR modalities

Key Requirements

  • PhD in immunology, cell biology, or related field
  • MS with 4+ years in cell therapy discovery
  • Proficiency with ELN, FlowJo, SnapGene, GraphPad
  • Understanding of assay acceptance criteria and basic statistics
  • BSL 2 biosafety practices
  • Awareness of research GxP and data integrity

Work Rights

Not specified

Tailored Resume

Cover Letter