Advisor/senior Advisor Linker-payload, Antibody-drug Conjugate And Bioconjugation Engineering

Eli Lilly

Indianapolis, Indiana, US
Base: $129,000 - $209,000; bonus/equity: compyny b...
Linker-payload (l-p) chemistry
Antibody-drug conjugate (adc) development
Bioconjugation process development
The current position focuses on “small” molecule Linker-payload (L-P) and bioconjugation chemistry and engineering challenges for ADC / AOC medicines development

Job Summary

  • The current position focuses on “small” molecule Linker-payload (L-P) and bioconjugation chemistry and engineering challenges for ADC / AOC medicines development.
  • The Advisor / Senior Advisor will collaborate with a diverse cross-functional team on phase appropriate development of small molecule chemistry and unit operations for L-P synthesis such as reactions, extractions, isolations (crystallization and amorphous precipitation), and chromatographic purification, and ADC / AOC bioconjugation process development including conjugation chemistry and tangential flow filtration and technical-transfer to clinical and commercial manufacturing.
  • The successful applicant is expected to contribute in the laboratory to develop data to support projects and for platform development.

Matching Summary

The current position focuses on “small” molecule Linker-payload (L-P) and bioconjugation chemistry and engineering challenges for ADC / AOC medicines development.

Salary

Base: $129,000 - $209,000; Bonus/Equity: company bonus; Benefits: comprehensive benefit program

Skills & Requirements

Must-have

  • Linker-payload (L-P) chemistry
  • Antibody-drug conjugate (ADC) development
  • Bioconjugation process development
  • Phase appropriate development
  • Laboratory experimentation

Nice-to-have

  • Mechanistic thinking and modeling
  • Data rich experimentation
  • Innovative platform technologies
  • Continuous processing
  • Automation solutions

Key Requirements

  • PhD in Chemical Engineering, Physical Chemistry, Chemistry, Biochemistry or related field
  • 0-5 years of experience in pharmaceutical or biotech industry

Work Rights

Not specified

Tailored Resume

Cover Letter